IGF-1 mediates many growth and repair effects downstream of GH. Research analogues (e.g. IGF-1 LR3, pegylated MGF contexts) modify half-life or local signalling — cite IGF-axis reviews for educational grounding.
EXPLAINER
Class explainer — IGF analogues
Research & laboratory use only
This article supports qualified researchers. It is not medical advice and must not be used to plan human or veterinary administration.
Primary literature
- Relationship between growth hormone in vivo bioactivity, the insulin-like growth factor-I system and bone mineral density in men and womenEndocrine Reviews / IGF axis (2008)
- Potency of Full-Length MGF to Induce Maximal Activation of the IGF-I R Is Similar to Recombinant Human IGF-I at High Molar ConcentrationsGrowth Hormone & IGF Research (2016)
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