GH AXIS

GHRH analogues — sermorelin, tesamorelin, CJC

TARA Research Desk · 2026-07-20 · 5 min read

Research & laboratory use only

This article supports qualified researchers. It is not medical advice and must not be used to plan human or veterinary administration.

GHRH analogues bind pituitary GHRH receptors to stimulate GH secretion. Tesamorelin has FDA labelling for a specific HIV-related indication — useful regulatory reading. Research analogues such as sermorelin and CJC-1295 (with or without Drug Affinity Complex) differ mainly in duration of receptor stimulation.

Approved-drug labels do not authorise research-chemical use in humans. Keep those domains separate in documentation.

Primary literature

Metabolic effects of a growth hormone-releasing factor in patients with HIVNew England Journal of Medicine (2007)
EGRIFTA (tesamorelin) — FDA prescribing informationDrugs@FDA (2019)
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormoneJournal of Clinical Endocrinology & Metabolism (2006)
Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?Clinical Interventions in Aging (2006)

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